Objective To investigate the influence of plasma crystalloid osmolality on short-term prognosis in patients with acute ST-segment elevation myocardial infarction (STEMI) in intensive care unit (ICU) of cardiovascular diseases. Methods STEMI patients in ICU were chosen from the Affiliated Hospital of Xuzhou Medical University from Mar. 2018 to Mar. 2021 and study variable was plasma crystalloid osmolality. The clinical end-point event was in-hospital all-cause mortality. The relationship between plasma crystalloid osmolality and in-hospital mortality was analyzed by using Lowess curve and bar chart. The data screened by single-factor analysis with difference with statistical significance was given a multi-factor Logistic regression analysis. Finally the predictive value of plasma crystalloid osmolality was reviewed by using ROC curve. Results There were 582 eligible patients with STEMI included in the study. Lowess curve and bar chart showed that there was a U-shaped relationship between plasma crystalloid osmolality and in-hospital all-cause mortality in STEMI patients. After corrected the clinical features related to in-hospital all-cause mortality, plasma crystalloid osmolality still was an independent predictive factor of mortality in STEMI patients (OR=1.06, 95%CI: 1.04~1.09, P<0.001). The results of ROC curve analysis showed that plasma crystalloid osmolality had some predictive value to in-hospital all-cause mortality in STEMI patients, and AUC was 0.70 (95%CI: 0.64~0.75, P<0.01). Conclusion Plasma crystalloid osmolality may be an independent risk factor of in-hospital all-cause mortality in STEMI patients in ICU. There is a U-shaped relationship between plasma crystalloid osmolality and in-hospital all-cause mortality, which has a higher predictive value to in-hospital mortality.
