Objective To analyze the risk factors of atrial fibrillation (AF) in people aged≥50 in a hospital based on propensity score matching (PSM) in order to provide guidance for AF prevention and control in this group of people. Methods The people group aged≥50 undergone healthy examinations were chosen from Department of Cardiology in the Fourth People's Hospital of Taizhou City from Feb. 2020 to Jan. 2022, and persons diagnosed as AF patients by electrocardiogram were selected into AF group. After PSM according to a ratio of 1: 4 in age and gender, the persons without AF were selected into non-AF group. After PSM, demographic data [body mass index (BMI), occupation, education background), disease history, life and behavior habits and biochemical indexes were compared between 2 groups. The risk factors of AF occurrence in people group aged≥50 were analyzed by using multi-factor Logistic regression analysis. Results Among 866 cases received ECG screening, 46 cases were diagnosed with AF, and the detection rate of AF was 5.31%. The AF patients (n=46) were included into AF group, and those without AF (n=184) were included into non-AF group. There were totally 230 patients included. The level of BMI, percentages of hypertension and coronary heart disease (CHD), and level of blood uric acid (BUA) were significantly higher (P<0.05), and level of high-density lipoprotein-cholesterol (HDL-C) was significantly lower in AF group than those in non-AF group (P<0.05). The results of multi-factor Logistic regression analysis showed that the major risk factors of AF in people group aged≥50 included higher BMI (OR=1.906, 95%CI: 1.036~3.506, P<0.05), hypertension history (OR=2.013, 95%CI: 1.122~3.610, P<0.05), CHD history (OR=2.226, 95%CI: 1.258~3.938, P<0.05) and higher BUA level (OR=2.483, 95%CI: 1.420~4.341, P<0.05). Conclusion The detection rate of AF was higher in people group aged≥50. The main risk factors include igher BMI, hypertension history, CHD history and higher BUA level.
