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基于倾向性评分匹配的某医院≥50岁人群的心房颤动危险因素分析

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摘要:

目的 基于倾向性评分匹配分析某医院≥50岁人群的房颤(AF)危险因素,以期为该类人
群AF的防控提供指导依据。方法 选择2020年2月至2022年1月于泰州市第四人民医院心内科进行健康检
查,年龄≥50岁的人群,将经心电图检查确诊为AF的患者纳入AF组内,按年龄、性别实施1:4比例倾向
性评分匹配后的非AF人群纳入非AF组。匹配后对两组人口统计学资料(体质指数、职业、学历)、疾病
史、生活行为习惯、生化指标进行比较,利用多因素Logistic回归分析法分析≥50岁人群AF发生的危险因
素。结果 在接受心电图筛查866例中,46例确诊为AF,AF检出率为5.31%;将46例AF患者纳入AF组,按
照非AF组选择程序,纳入非AF患者184例,共纳入230例。AF组体质指数、高血压、冠心病、血尿酸水
平明显高于非AF组(P<0.05),高密度脂蛋白胆固醇水平明显低于非AF组(P<0.05)。Logistic回归分
析结果显示,年龄≥50岁人群发生AF的主要危险因素为高体质指数(OR=1.906,95%CI:1.036~3.506,P
<0.05)、高血压病史(OR=2.013,95%CI:1.122~3.610,P<0.05)、冠心病病史(OR=2.226,95%CI:
1.258~3.938,P<0.05)和高血尿酸水平(OR=2.483,95%CI:1.420~4.341,P<0.05)。结论 年龄≥50岁
人群AF检出率较高,主要危险因素为高体质指数、高血压、冠心病和高血尿酸。

Abstract:

Objective To analyze the risk factors of atrial fibrillation (AF) in people aged≥50 in a hospital based on propensity score matching (PSM) in order to provide guidance for AF prevention and control in this group of people. Methods The people group aged≥50 undergone healthy examinations were chosen from Department of Cardiology in the Fourth People's Hospital of Taizhou City from Feb. 2020 to Jan. 2022, and persons diagnosed as AF patients by electrocardiogram were selected into AF group. After PSM according to a ratio of 1: 4 in age and gender, the persons without AF were selected into non-AF group. After PSM, demographic data [body mass index (BMI), occupation, education background), disease history, life and behavior habits and biochemical indexes were compared between 2 groups. The risk factors of AF occurrence in people group aged≥50 were analyzed by using multi-factor Logistic regression analysis. Results Among 866 cases received ECG screening, 46 cases were diagnosed with AF, and the detection rate of AF was 5.31%. The AF patients (n=46) were included into AF group, and those without AF (n=184) were included into non-AF group. There were totally 230 patients included. The level of BMI, percentages of hypertension and coronary heart disease (CHD), and level of blood uric acid (BUA) were significantly higher (P<0.05), and level of high-density lipoprotein-cholesterol (HDL-C) was significantly lower in AF group than those in non-AF group (P<0.05). The results of multi-factor Logistic regression analysis showed that the major risk factors of AF in people group aged≥50 included higher BMI (OR=1.906, 95%CI: 1.036~3.506, P<0.05), hypertension history (OR=2.013, 95%CI: 1.122~3.610, P<0.05), CHD history (OR=2.226, 95%CI: 1.258~3.938, P<0.05) and higher BUA level (OR=2.483, 95%CI: 1.420~4.341, P<0.05). Conclusion The detection rate of AF was higher in people group aged≥50. The main risk factors include igher BMI, hypertension history, CHD history and higher BUA level.

基金项目:

江苏省泰州市海陵区科技发展计划(社会发展)项目
(泰海科发[2020]5号)

参考文献:

  • 2008

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