目的 对钠-葡萄糖协同转运蛋白2抑制剂（SGLT2i）干预心力衰竭的相关文献进行可视化分析，探讨其研究进展与热点。方法 检索Web of Science Core Collection数据库（WOSCC），将检索到有关SGLT2i干预心力衰竭的数据导入Cite Space绘制知识图谱，对作者、机构、国家和关键词进行可视化分析。结果 SGLT2i干预心力衰竭的有关文献发文量从2016年起呈逐年上升趋势。发文量靠前的作者有Silvio E Inzucchi，Subodh Verma，Darren K Mcguire等，国家有美国、英国、加拿大等，机构有多伦多大学、哈佛医学院、哈佛大学医学院附属布列根和妇女医院等。关键词分析得出二肽基肽酶4抑制剂（DPP-4i）和SGLT2i、EMPA-REG OUTCOME研究，胰高血糖素样肽-1受体激动剂（GLP-1RA）和心血管死亡率预后等为研究热点。结论 通过文献计量学分析，SGLT2i干预心力衰竭领域目前正处于研究高热期，但发文量不多，需继续完善相关研究，加强各个国家和机构的合作。研究热点更新较快，研究有很大的发展空间。

Objective To conduct a visualized analysis on literature related to sodium-glucose cotransporter 2 inhibitor (SGLT2i) intervening heart failure (HF), and discuss the progress and hotpots in this research field. Methods The database of Web of Science Core Collection (WOSCC) was retrieved, then the retrieved data related to SGLT2i intervening HF was imported into Cite Space software for drawing knowledge graph, and authors, institutions, countries and keywords were given a visualized analyzed. Results The quantity of literature related to SGLT2i intervening HF began to show a upward trend year by year since 2016. Silvio E Inzucchi, Subodh Verma and Darren K Mcguire were top authors in issued paper quantity. The top countries were the United States, the United Kingdom and Canada. The top institutions were University of Toronto, Harvard Medical School, Brigham and Women’s Hospital affiliated to Harvard Medical School, etc. The results of keyword analysis showed that Dipeptidyl peptidase 4 inhibitor (DPP-4i), SGLT2i, EMPA-REG OUTCOME study, glucagon-like peptide-1 receptor agonist (GLP-1RA) and prediction on cardiovascular mortality were research hotpots. Conclusion The bibliometric analysis shows that research field of Sglt2i intervening HF is currently in a hot period. However, the quantity of published papers on SGLT2i intervening HF is not enough. It is necessary to continue to improve relevant studies and strengthen the cooperation among various countries and institutions. The research hotspots are updated quickly, and there are still great possibilities for developing the studies.

国家自然科学基金项目(82074409)